You will receive the result of your GeneXmatch in an email from us and your result will be one of the following options:
Yes. Even without a family history with a recessive disease. We know that all humans are carriers of one or more recessive diseases. Usually the individuals have no knowledge about being a carrier since carriers of recessive diseases are healthy.
Individuals who suffer from a disease with recessive inheritance have two mutated copies of the disease gene, one mutated gene from each parent.
As the parents have only one mutated copy, they are healthy carriers. If both parents are carriers of the same disease, their risk of having an affected child is 25% in each pregnancy. Males and females are equally often affected.
In diseases with X-linked inheritance, the mutated gene is located on the female sex chromosome (the X chromosome).
Males have one X chromosome and one Y chromosome. Females have two X chromosomes. A female with one mutated copy of the disease gene is a healthy carrier. Males with one mutated copy are affected.
If a woman is a carrier of an X-linked disease her risk of having an effected child is 25 % in each pregnancy since only half of her sons will be affected and her daughters will either be healthy carriers or healthy non-carriers.
The residual risk of having a child with a disease included in the GeneXmatch panel will be almost 0.
We test for diseases with the highest frequency in the population. 97 of these diseases are well known critical diseases recommended by The American College of Obstetricians and Gynaecologists. The rest of the diseases are less frequent but sufficiently serious to be included.
Based on population studies, in average 1:100 couples have a reproductive risk for a recessive disease (=1%). Moreover, the woman’s risk of being a carrier of one of the investigated X-linked diseases is up to 1:200.
Almost all our donors are available for GeneXmatch – they are clearly marked on the website.
No, GeneXmatch is only made for pre-conceptional screening – that is i.e. before you get pregnant.
No, it is not possible. We don’t have the genetic data on sperm donors from other sperm banks.
You are paying for a test that includes in total more than 400 recessive and X-linked diseases. The fee also covers shipping of the saliva kit to your address and eventual genetic counselling. The fee does not cover the shipping from your address to the laboratory.
GeneXmatch should be purchased at the same time as you order sperm from your chosen donor.