What we screen for


European Sperm Bank only accepts 5-7% of all donor applicants. We check diligently for high-quality sperm as this is important for a successful pregnancy. We carry out extensive genetic testing to help you feel confident about your choice. In many ways, our testing exceeds the requirements of the EU Tissue Directive.

Initial selection criteria

  • Sperm quality and sperm count
  • Age (18-39 years)
  • Physical examination by a trained GP
  • Personality

Screening of blood and urine (* tests performed with a 90 days interval)

  • ABO-Rh blood typing
  • Biochemistry panel
  • Complete blood count
  • HIV I/II *
  • HTLV I/II *
  • Hepatitis B *
  • Hepatitis C *
  • Syphilis *
  • CMV IgG/IgM *
  • Chlamydia *
  • Gonorrhoeae *
  • Additional testing based upon donor’s travel activities
  • Zika
  • West Nile Fever

Genetic risk assessment and testing

Donors who have an abnormal chromosome analysis (karyotype) and/or are carriers of any of the following diseases are NOT accepted in our donor programme.

    All prospective donors
  • Third to fourth-generation family medical history reviewed by a trained genetic specialist
  • Chromosome analysis (karyotyping)
  • Cystic fibrosis screening for mutations in the cystic fibrosis gene
  • SMA (spinal muscular atrophy) in all active donors from January 2015. If you want to know test status for a specific donor, please contact us.
  • Non-syndromic hearing loss and deafness (GJB2 related) in new donors from June 2016. If you want to know test status for a specific donor, please contact us.
  • Alpha and beta thalassaemias and sickle cell disease (screening by HPLC and red blood cell haematology). Less than 1 in 1,000 are carriers for this disease in the Northern European population.

  • Prospective donors of Jewish or French-Canadian ancestry
    • Bloom syndrome
    • Canavan Disease
    • Familial Dysautonomia
    • Fanconi Anaemia type C
    • Gaucher Disease
    • Mucolipidosis type IV
    • Niemann-Pick Disease
    • Tay-Sachs Disease